Inhibition of selectin binding by colloidal gold with functionalized shells.
نویسندگان
چکیده
Gold colloids with terminally functionalized sulfated thiol shells were found to bind to P- and L-selectins with IC(50) values in the picomolar range; branched acyclic epitopes show the highest affinity, whereas a sulfated carbohydrate mimetic provides the best selectivity.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 8 شماره
صفحات -
تاریخ انتشار 2009